Quantitative computed tomography assessment of bronchiolitis obliterans syndrome after lung transplantation
نویسندگان
چکیده
منابع مشابه
Chest computed tomography in bronchiolitis obliterans after bone marrow transplantation
Radiol Bras. 2017 Mai/Jun;50(3):IX Bronchiolitis obliterans (BO) is an inflammatory disease of the small airways, resulting from damage to the lower respiratory tract. The presence of inflammation and fibrosis of the terminal and respiratory bronchioles results in narrowing or complete obliteration of the airway lumen, leading to chronic airflow obstruction. Histologically, BO is characterized ...
متن کاملBronchiolitis Obliterans After Lung Transplantation
ing lung transplantation is 71%, and 46% of trans¬ plant recipients will survive at least 5 years.1 Al¬ though infections, medication-related adverse events, and malignancies remain important compli¬ cations, prolonged survival is limited predominantly by bronchiolitis obliterans (RO), a condition that was associated with transplantation more than a decade ago.25 Data suggest that at least 50% ...
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Bronchiolitis obliterans syndrome (BOS) is a severe complication after lung transplantation (LTX). In a retrospective cohort study 12 stable healthy recipients (non-BOS) and eight patients with BOS were enrolled after LTX and matrix metalloproteinases (MMP)-9, TIMP-1 and cell characteristics in bronchoalveolar lavage (BAL) samples (n = 145) were analysed. BALs from patients with BOS were furthe...
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Bronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent ...
متن کاملBronchiolitis obliterans syndrome: the Achilles' heel of lung transplantation.
Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders. Unfortunately, chronic lung allograft dysfunction (CLAD), most commonly manifest as bronchiolitis obliterans syndrome (BOS), continues to be highly prevalent and is the major limitation to long-term survival. The pathogenesis of BOS is complex and involves alloimmune and nonalloimmune pathways. Clinica...
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ژورنال
عنوان ژورنال: Clinical Transplantation
سال: 2017
ISSN: 0902-0063
DOI: 10.1111/ctr.12943